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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
ECI1_HUMAN
USC-OGP 2-DE database
:
ECI1_HUMAN
ECI1_HUMAN
General information about the entry
View entry in simple text format
Entry name
ECI1_HUMAN
Primary accession number
P42126
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Enoyl-CoA delta isomerase 1, mitochondrial; EC=5.3.3.8; AltName: Full=3,2-trans-enoyl-CoA isomerase; AltName: Full=Delta(3),Delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Dodecenoyl-CoA isomerase; Flags: Precursor;.
Gene name
Name=ECI1
Synonyms=DCI
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0505
:
pI=5.64; Mw=27760
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0788
:
pI=5.91; Mw=29973
Cross-references
UniProtKB/Swiss-Prot
P42126; ECI1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
ECI1_HUMAN
Primary accession number
P42126
Secondary accession number(s)
A8K512 Q13290 Q7Z2L6 Q7Z2L7 Q9BUB8 Q9BW05 Q9UDG6
Sequence was last modified on
November 1, 1995 (version 1)
Annotations were last modified on
March 15, 2017 (version 169)
Name and origin of the protein
Description
RecName: Full=Enoyl-CoA delta isomerase 1, mitochondrial; EC=5.3.3.8; AltName: Full=3,2-trans-enoyl-CoA isomerase; AltName: Full=Delta(3),Delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Dodecenoyl-CoA isomerase; Flags: Precursor;
Gene name
Name=ECI1
Synonyms=DCI
Encoded on
Name=ECI1; Synonyms=DCI
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Complete proteome
;
Direct protein sequencing
;
Fatty acid metabolism
;
Isomerase
;
Lipid metabolism
;
Mitochondrion
;
Reference proteome
;
Transit peptide
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
Z25820; CAA81065.1
; -; mRNA
EMBL
Z25821; CAA81066.1
; -; Genomic_DNA
EMBL
Z25822; CAA81066.1
; JOINED; Genomic_DNA
EMBL
Z25823; CAA81066.1
; JOINED; Genomic_DNA
EMBL
Z25824; CAA81066.1
; JOINED; Genomic_DNA
EMBL
AK291127; BAF83816.1
; -; mRNA
EMBL
CH471112; EAW85524.1
; -; Genomic_DNA
EMBL
BC000762; AAH00762.1
; -; mRNA
EMBL
BC002746; AAH02746.1
; -; mRNA
EMBL
BC020228; AAH20228.1
; -; mRNA
EMBL
BC019316; AAH19316.1
; -; mRNA
EMBL
L24774; AAA35485.1
; -; mRNA
CCDS
CCDS10464.1; -. [P42126-1]
; .
CCDS
CCDS58410.1; -. [P42126-2]
; .
PIR
A55723; A55723
; .
RefSeq
NP_001171500.1; NM_001178029.1. [P42126-2]
; .
RefSeq
NP_001910.2; NM_001919.3. [P42126-1]
; .
UniGene
Hs.403436; -
; .
PDB
1SG4; X-ray
; 1.30 A; A/B/C=43-302
PDBsum
1SG4; -
; .
ProteinModelPortal
P42126; -
; .
SMR
P42126; -
; .
BioGrid
108000; 9
; .
IntAct
P42126; 4
; .
MINT
MINT-3015421; -
; .
STRING
9606.ENSP00000301729; -
; .
DrugBank
DB03127; Benzamidine
; .
DrugBank
DB02910; Octanoyl-Coenzyme A
; .
SwissLipids
SLP:000001184; -
; .
iPTMnet
P42126; -
; .
PhosphoSitePlus
P42126; -
; .
SwissPalm
P42126; -
; .
BioMuta
ECI1; -
; .
DMDM
1169204; -
; .
OGP
P42126; -
; .
EPD
P42126; -
; .
MaxQB
P42126; -
; .
PaxDb
P42126; -
; .
PeptideAtlas
P42126; -
; .
PRIDE
P42126; -
; .
TopDownProteomics
P42126-1; -. [P42126-1]
; .
TopDownProteomics
P42126-2; -. [P42126-2]
; .
Ensembl
ENST00000301729; ENSP00000301729
; ENSG00000167969. [P42126-1]; .
Ensembl
ENST00000562238; ENSP00000456319
; ENSG00000167969. [P42126-2]; .
GeneID
1632; -
; .
KEGG
hsa:1632; -
; .
UCSC
uc002cpr.4; human. [P42126-1]
; .
CTD
1632; -
; .
DisGeNET
1632; -
; .
GeneCards
ECI1; -
; .
HGNC
HGNC:2703; ECI1
; .
HPA
HPA041746; -
; .
HPA
HPA043227; -
; .
MIM
600305; gene
; .
neXtProt
NX_P42126; -
; .
OpenTargets
ENSG00000167969; -
; .
PharmGKB
PA27173; -
; .
eggNOG
ENOG410ISNQ; Eukaryota
; .
eggNOG
COG1024; LUCA
; .
GeneTree
ENSGT00390000005678; -
; .
HOVERGEN
HBG001112; -
; .
InParanoid
P42126; -
; .
KO
K13238; -
; .
OMA
ENDKSFR; -
; .
OrthoDB
EOG091G0I32; -
; .
PhylomeDB
P42126; -
; .
TreeFam
TF314436; -
; .
BRENDA
5.3.3.8; 2681
; .
Reactome
R-HSA-77288; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
; .
UniPathway
UPA00659; -
; .
ChiTaRS
ECI1; human
; .
EvolutionaryTrace
P42126; -
; .
GenomeRNAi
1632; -
; .
PRO
PR:P42126; -
; .
Proteomes
UP000005640; Chromosome 16
; .
Bgee
ENSG00000167969; -
; .
CleanEx
HS_DCI; -
; .
ExpressionAtlas
P42126; baseline and differential
; .
Genevisible
P42126; HS
; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005743; C:mitochondrial inner membrane
; IEA:Ensembl; .
GO
GO:0005759; C:mitochondrial matrix
; NAS:UniProtKB; .
GO
GO:0005739; C:mitochondrion
; IDA:UniProtKB; .
GO
GO:0004165; F:dodecenoyl-CoA delta-isomerase activity
; NAS:UniProtKB; .
GO
GO:0004300; F:enoyl-CoA hydratase activity
; IBA:GO_Central; .
GO
GO:0016860; F:intramolecular oxidoreductase activity
; TAS:Reactome; .
GO
GO:0006635; P:fatty acid beta-oxidation
; NAS:UniProtKB; .
Gene3D
3.90.226.10; -
; 1; .
InterPro
IPR029045; ClpP/crotonase-like_dom
; .
InterPro
IPR001753; Crotonase_core_superfam
; .
InterPro
IPR018376; Enoyl-CoA_hyd/isom_CS
; .
Pfam
PF00378; ECH_1
; 1; .
SUPFAM
SSF52096; SSF52096
; 1; .
PROSITE
PS00166; ENOYL_COA_HYDRATASE
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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